Seven strangers, each with a secret to bury, meet at Lake Tahoe's El Royale, a rundown hotel with a dark past. Over the course of one fateful night, everyone will have a last shot at redemption - before everything goes to hell.

In a cold and remote landscape, two strangers struggle to repair their broken pasts.A young man is on parole after serving time for attempting to murder the man who killed his girlfriend in a hit and run. A woman is released from a psychiatric facility far from her homeland. These two damaged strangers cross paths in the mountains in winter and fall into a complex intimate relationship, putting to the test their capacity to trust and heal.

When Eddie Brock acquires the powers of a symbiote, he will have to release his alter-ego "Venom" to save his life.